約 5,332,696 件
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キャラクター名 SORAYU-姶良Pスキル：★愛情 ：★自爆度 ：★★★★★ メイン職業 パニカス ランカークラス Class D キルクラス Class D デット数 所属部隊名 VIPRISK 名言 勝ち馬属性 戦闘スタイル ナイトで歩兵突き 総評 そらゆわんこっちゃない 本人への要望 自爆乙 本人より 頭がフッコーしそうだよぉっっ 7月3日早朝、▽さつき▽に「暴言を吐かれたので運営に報告したい」と、 B鯖スレに初心者を装って書き込んだ所、初心者の振りが余りにも稚拙なため即バレ、 同じゲブ民からツッコミが入り、当人である▽さつき▽にすらSNSで特定されてしまう。 +詳細表示 2008年7月3日早朝、このようなレスがB鯖スレに投下される 903 名前： 既にその名前は使われています 投稿日： 2008/07/03(木) 04 16 58.15 ID P/8EpFTJ 馬鹿とかあほぉかとか言われたんだけど これSS撮って提出したらBANなるかな？ 904 名前： 既にその名前は使われています [sage] 投稿日： 2008/07/03(木) 04 19 16.88 ID QUcTWyis ゲーム内でやり返しつつBBSでも叩く 他の国は微妙だが、ゲブには効くんじゃね？BBS国家だし 903 BANならんでも少なくとも警告措置とかは行くんじゃね？ 908 名前： 既にその名前は使われています [sage] 投稿日： 2008/07/03(木) 04 23 50.46 ID P/8EpFTJ 904 ちゃんと対応してくれる運営なのか でも俺もちょっと悪いことしたって反省してる ずっとハイドばれたりパニくらったりしてむかついて… でもFEZ始めて4日の俺には何もやりかえせないから とりあえず召還なって味方が押しだした時に ナイトの小ランスでボコボコにして逃げれなくしたんだ… でも低レベルでも遊べるのがFEZだろ…それで暴言吐かれるとか気分悪いわ ▽さつき▽ ちなみにこいつなたぶん黄色の国に所属してるお ここでゲブ民から痛烈なツッコミ3連発が入る。 929 名前： 既にその名前は使われています [sage] 投稿日： 2008/07/03(木) 07 58 45.99 ID tUVwlUz/ 初めて4日の割に黄色い国という表現 （このキャラを育て）始めて4日だが（元来PSがないので）さつきにパニられるわハイド暴かれるわで散々 （初心者装おって）スレに報告するお てなところだろうな 大方、首都北の階段族だ アイツらさつきに関してたまに範囲チャたれながしてるからな ゲブの最大の癌であることは確かだ 935 名前： 既にその名前は使われています [sage] 投稿日： 2008/07/03(木) 08 31 43.13 ID tUVwlUz/ 始めて4日のガチ初心者がナイトで歩兵粘着の発想はちと無理がある ゲブで初心者受け入れて基本から教えてる部隊なんて絶無 階段族の奴らはさつきに粘着してるからまず間違いないだろ 940 名前： 既にその名前は使われています [sage] 投稿日： 2008/07/03(木) 08 46 03.88 ID tUVwlUz/ 以前、階段族の奴らとさつきは範囲で煽りあいをしてたからな 今はやってねーけど あれもさつきにパニられて顔真っ赤になったアイツらがレイプ戦で粘着して煽ったのが始まり マジ消えてくんねーかなアイツら ツッコミを書き込んだのは恐らく南区のゲブ民だと思われるが、 最初の書き込みの矛盾点を次々と暴いていく様が痛快である。 結局、現段階でレベル33スカ、ランク4という初心者か微妙なキャラといえる。 他の戦場でもナイトで歩兵突きをしているらしく、敵を全チャ煽りした際には、 「ナイトで歩兵突く奴が何を言うか」と同じゲブ民からも全チャで突っ込まれる失態。 BゲブのクズはBBS工作が下手だという点と、クズに煮え湯を飲まされている一般層からの 自浄作用が思った以上に強いという点が浮き彫りになった例である。 それにしても、所属部隊がVIPRISKであり初心者でも無かった点を見るに ID tUVwlUz/の推理力には目を見張るものがある。 マルクティスイベントでの不正騒動以来（参考：B鯖黒いマルク三人衆、ハゲス）、衰退の一途を辿るゲブランド帝国の再建に立ち上がった晒しスレ民がいた。 ゲブを救う（ｷﾘｯ 部隊の創設をBゲブ晒しスレで呼びかけるも、スレ民の反応はイマイチ。 賛同した極僅かの晒し民にも、部隊長が短カスの上、＜nEt4゛holic＞という厨丸出しの部隊名であったことから拒否反応を示すものが続出。 メインキャラを晒せという流れの中、以下のレスが投下された。 951 ：名無しさん＠ｺﾞｰｺﾞｰｺﾞｰｺﾞｰ！：2009/02/25(水) 23 38 53 ID gXmHfzKn0 nEt4゛holicで検索した ttp //littletoe.blog25.fc2.com/blog-entry-18.html SAでSORAYUなる人物が創立したクラン名と一緒だった ん？ SORAYU？ そう、以前、初心者を装って▽さつき▽を貶めようとするも光の速さでスレ民に矛盾点を暴かれ 挙句逆晒しをくらったSORAYU-姶良その人であった。 そらゆわんこっちゃない、と誰が上手いことを言えと、の流れになり、晒しスレ部隊創設が立ち消えになったのは言うまでも無い。 本人はレイスで出したスコアを「俺の実力はこんなもんじゃーい！」とスレに貼り付けるなど、終始厨っぷりを見せ付けた。 メインキャラでの動きはお世辞にも上手いとは言いがたい短カスであり、以降の晒し民の反応が一気に冷めたのは語るまでもないだろう。 気に入らない相手を虚言で貶めようとする人間性でもって、ゲブの何を救うつもりであったのか。 BBS工作どころか復興部隊すらまともに作れず、ゲブを救う前に足元を掬われた形となっている。 SORAYUの存在がゲブそのものじゃないか、と言われても一切の反論はできない。 現在はいち早くF鯖エルに逃げ出して Felix_SorayuAira という短カスでライダーをしているようだ。 これも速攻でバレているように、少しは違う名前にしようとかそういう知恵は回らないようである。 彼の足元はいつまでお留守なのか、興味は尽きない。 SORAYU「復興部隊を作ろうと思ったその日にメインバレするなんて、頭がフッコーしそうだよぉ！」 さらにvipskypeスレでも 性欲の塊・熊の片栗粉X skypeID sora-y-u webカメラを繋ぐと脱げと強要してくる性欲の塊 脱がないと得意のショタ声でグズりだす 愛用のオナニーグッズはくまのぬいぐるみいと片栗粉X として大活躍している 54 名前：以下、名無しにかわりましてVIPがお送りします[] 投稿日：2009/03/10(火) 13 01 21.40 ID 7QTPuIvC0 sora-y-u 暇です 彼にHNを変えるという考えはないのだろうか？
https://w.atwiki.jp/mrfrtech/pages/17.html
Market Highlights The adoption of the concept of online meetings by various organizations is spurring the online meeting software market 2020. The software reports are formed by Market Research Future, which covers market alternatives for progress. The Global Online Meeting Software Market is expected to register a CAGR of 11.1% during the forecast period of 2020–2027. There are various factors contributing to the growth of the global online meeting software such as the increasing digitalization and urbanization which is increasing the adoption of online meeting software among the enterprises to reduce the distance between the clients globally. The surge in the concept of work from home due to the ongoing coronavirus pandemic, the market share of online meeting software is estimated to rise steadily in the impending period. Their surging application in conducting webinars and for web conferencing is predicted to direct the online meeting software market in the forecast period. Segmental Analysis The global online meeting software market has been segmented based on component, deployment, organization size, end user, and region. By component, the market has been segmented into software and services. By deployment, the market has been segmented into cloud-based and on-premise By organization size, the market has been segmented into large enterprises and SMEs. By end user, the market has been segmented into BFSI, IT telecom, government, healthcare, manufacturing, and others By region, the market has been segmented into North America, Europe, Asia-Pacific, and the rest of the world. Request a Free Sample @ https //www.marketresearchfuture.com/sample_request/8297 Detailed Regional Analysis The global online meeting software market is estimated to grow at a significant rate in the future. The geographical analysis of online meeting software market has been conducted for North America, Europe, Asia-Pacific, and the rest of the world. North America dominates the global online meeting software market, by region, due to the early adoption of the web conferencing services and online meeting. Additionally, there are various companies present in the region who offers various online meeting software and services which is driving the growth of the market. Additionally, high internet speed and developed infrastructure which increases the demand for the online meeting software market in the region. The US accounts the largest market share in the region due to presence of various industries and end-users in the region who are using these software and services such as BFSI, IT telecom, government agencies, and others. Whereas, Canada is expected to be the fastest-growing country in the region during the forecast period. Europe accounts the second-largest market share in the online meeting software market due to presence of various industries such as automotive, BFSI, IT telecom, and others which is driving the market. Additionally, the presence of various countries such as the UK, Germany, France, Italy, and others in the region are the major contributors in the global online meeting market. Additionally, the increasing ownership of smartphones has also accelerated the market growth in the region as the users can attend the web conference with smartphones irrespective of their location. Asia-Pacific is expected to be the fastest-growing region during the forecast period due to increasing advancement in terms of technology, urbanization, and digitalization. The present companies and upcoming startups are adopting online meeting software to increase their client conversion. Additionally, the SMEs and large enterprise are also using this software to reduce their spend on travel and increase the productivity and efficiency of the work without spending much on traveling. China is expected to be the dominating country in the region whereas India is accounted to be the fastest-growing country during the forecast period. Rest of the world is segmented as South America and Middle East Africa is expected to be growing with a significant CAGR during the forecast period due to development of infrastructure and investments made by various industries in the region. Additionally, the subsidiaries and startups are using smartphones for online meeting to conduct training and conferencing. Competitive Analysis The capability of contenders to influence change in the market is increasing at a stable rate in the impending period. The support from government bodies around the world is rising because the market needs an extra stimulus to achieve normalcy in such a scenario. The disharmony in the forces of demand and supply are estimated to create a slow growth background in the market. Furthermore, the need to adopt a rapid and cost-effective method of operation is estimated to profile the market in the impending period. The emphasis on innovation is estimated to rise in the coming years, as the consumer needs have to be addressed in a better manner to ensure the resurgence of the global market. Also, the need to encourage business to include the environmental impact of their decisions is estimated to shape the progress of the market in future. The need to mitigate losses sustained by the current public health crisis is estimated to be the sole focus of the market contenders in the upcoming years. The eminent contenders in the online meeting software market are Nextiva (US), RingCentral, Inc. (US), Amazon Web Services, Inc. (US), Zoho Corporation Pvt. Ltd. (India), Jive Communications (US), Vonage (US), Ooma, Inc. (US), FluentStream Technologies, LLC (US), Zoom Video Communications, Inc. (US), LogMeIn, Inc (US), Cisco Systems (US), Dialpad, Inc. (US), 8x8, Inc. (US), IBM Corporation (US), Microsoft Corporation (US) among others. Browse Full Report Details @ https //www.marketresearchfuture.com/reports/online-meeting-software-market-8297 Table of Contents 1 Executive Summary 2 Scope of The Report 2.1 Market Definition 2.2 Scope of The Study 2.2.1 Research Objectives 2.2.2 Assumptions Limitations 2.3 Market Structure Continued… Similar Report Application Management Services Market By Service-Type (System Integration, Consulting Services, Modernization Services, And Others), By Organization Size, By Deployment, And By End-Users Open Source Intelligence (OSINT) Market By Security Type (Human Intelligence, Content Intelligence, Dark Web Analysis, Link/Network Analysis, Data Analytics, Text Analytics, Artificial Intelligence, Big Data, Others), Technology (Bid Data Software, Video Analytics, Text Analytics, Visualization Tool, Cyber Security, Web Analysis, Social Media Analysis, Others), Application (Military Defense, Homeland Security, Private Sector, Public Sector, National Security, Others) About Market Research Future At Market Research Future (MRFR), we enable our customers to unravel the complexity of various industries through our Cooked Research Report (CRR), Half-Cooked Research Reports (HCRR), Raw Research Reports (3R), Continuous-Feed Research (CFR), and Market Research Consulting Services. Contact Market Research Future (Part of Wantstats Research and Media Private Limited) 99 Hudson Street, 5Th Floor New York, NY 10013 United States of America 1 628 258 0071 (US) 44 2035 002 764 (UK) Email sales@marketresearchfuture.com Website https //www.marketresearchfuture.com #market #research #industry #data #growth #trend #report #analyis #share #marketing #forecast #digital #geographic #demographic #gnews Plugin Error キーワードを入力してください。 #tech #researchreport #marketreport #futrue
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Ace Attorney Investigations Miles Edgeworth Preview for the Nintendo DS from 1UP.comhttp //www.1up.com/do/previewPage?cId=3177783 p=39 sec=PREVIEWS 02/02/2010 1UP Mr. Eshiro, you re the producer on Ace Attorney Investigations, but could you tell us a little more about your role in the game s development?1UP：江城さんは逆転検事のプロデューサーですが、もうちょっとこのゲームでの役割について教えてください。Motohide Eshiro I started as co-producer on the second and third Ace Attorney games, but this is my first time in the series as full producer. Mostly, I look over the overall product schedule and budget. I make sure everything s coming in on time -- things like that.江城元秀：逆転裁判との関わりは、DS版逆転裁判2と3の共同プロデューサーとしての役割が始まりですが、これはプロデューサーとしての初めての仕事でもありました。大まかには、私は全てのスケジュールと予算・経費を統括します。全てが予定通りに動くかを確認します。Another big part of my job is focusing on the overall quality of the game. While the director focuses on specific aspects -- fine-tuning the small details -- my job is more to look at the big picture. To make sure that everything fits in well with whole concept. I look at it like the average user and ask myself, Will the player enjoy this? 他の大きな仕事としては、ゲームの全ての質に焦点を当てています。ディレクターがある局面――細かい部分の微調整――に集中している時、私の仕事は全体を見ることです。全ての事象が、全体と調和しているかの確認です。私は1ユーザーとしてゲームを見て、私自身に確認します。「プレイヤーはこれを楽しいと思うだろうか？」And of course, doing promotion for the game, like traveling abroad to give interviews.そしてもちろん、ゲームの宣伝もします。海外に出向いてインタビューを受けたり。1UP Your current position sounds very different from your previous role as director on Shadow of Rome and Onimusha...1UP：あなたの現在の仕事は、以前のSHADOW OF ROMEや鬼武者のディレクターとしての役割とずいぶん異なるようですが。ME Yeah, Ace Attorney is a very different type of game, but I really wasn t thinking of it as something completely different. During my school days, I used to play a lot of PC-based text adventures. I really loved those back then, and I ve always been a huge fan of adventure games.江城：ええ、逆転裁判はゲームとしては異なるタイプですが、私は完全に異なるものとは思っていません。私は学生時代、PCでテキストアドベンチャーを多くプレイしたものです。私はそういうゲームが好きで、アドベンチャーゲームの大ファンでした。When I was a director, I was able to make action games like Onimusha and Shadow of Rome, but I just didn t have the opportunity to make my own adventure game. But when I switched roles to producer on Ace Attorney, I finally got the chance to make the types of games I loved playing when I was younger.私はディレクターとして、アクションゲームの鬼武者とSHADOW OF ROMEを制作しましたが、アドベンチャーゲームを創る機会はありませんでした。しかし逆転裁判のプロデューサーになって、とうとうアドベンチャーゲームの制作に関われることになったのです。1UP Do you think your time working with such action heavy games has changed the way you approached Ace Attorney Investigations?1UP：そのようなアクションゲームの仕事を制作していた時から比べ、逆転検事へのアプローチには変化がありましたか？ME Definitely, there s been some influence. Of course, in text-based games there s always some level of interactivity. But working in action games, I had firsthand experience in how to lay out a scene. For example, if you ve got a character moving somewhere, the background has to scroll and move smoothly.江城：確かに、少しは影響がありました、もちろん、テキストベースのゲームでは、常にそれなりの会話があります。しかしアクションゲームの制作では、私はシーン毎のレイアウトをどうするかといったことを経験しました。例えば、キャラクターをどこかに動かす時、背景はなめらかにスクロールしなければなりません。I think I was able to transfer some of that experience into Ace Attorney Investigations. When you move Edgeworth around, you re not going to run into weird scrolling issues; you re not going to see awkward movements, or things like that, and I attribute that to my action game experience.そういった経験を、逆転検事に生かすことができたと思います。あなたがプレイした時、御剣を動かしても妙なスクロールを見たり、ぎこちない動きを見たりすることはないでしょう。そういったことは、アクションゲームの制作による経験からだと考えています。1UP Speaking of adventure games, over the past few years in America, we ve seen a bit of a revival of that genre with games like Sam Max and Monkey Island. Do those come to Japan at all?1UP：アドベンチャーゲームについてですが、アメリカでは過去、Sam MaxやMonkey Islandのようなゲームがリバイバルしています。日本ではどうですか？ME I don t think they do. But when I think about PC adventure games, I think about the really old titles. Of course, Myst was a popular title everywhere, but I really enjoyed Mystery House. I can t think of other specific titles right at the moment, but just really old games, or games like Portopia, which never came out outside Japan. I really haven t tried out any recent adventure games. Even in Japan, they ve never remade some of my favorite titles, like Snatcher.江城：日本ではなかったと思います。しかし、私がPCのアドベンチャーゲームについて考える時、私は本当に古いタイトルについて思いを巡らせます。もちろん、Mystは有名ですが、私はMystery Houseが楽しかった。他の具体的なタイトルは思い出せないけれど、日本以外では発売されなかったポートピア連続殺人事件が好きです。私は最近のアドベンチャーゲームはプレイしていません。日本でさえ、スナッチャーのような私の好きなゲームのいくつかはリメイクされていません。With Mystery House, that was a game I played when I was still in college -- but it only came out in English. I didn t immediately understand half of what was written; maybe just a word like take, and then I d have to look up the rest to understand what I was able to take. So I d play along with a dictionary; it was almost like studying, but a lot more fun.Mystery Houseは、私が大学生のころにプレイしたゲームでした――しかし英語版しかありませんでした。私は書いてあることの半分も理解できませんでした。「take」というワードがあっても、何が取得できるのか、調べなくてはなりませんでした。そのため、私は辞書を片手にプレイしていました、それはまるで勉強みたいでしたが、楽しみでもありました。But Portopia is a game that s really stuck with me over the years. Are you ok with spoilers?しかし、ポートピア連続殺人事件は長年楽しく遊べたゲームです。ネタバレは大丈夫？1UP I think the game s old enough that that s ok.1UP：昔のゲームだから大丈夫。ME Well, the detective that you work with, the big twist at the end is that he s the criminal. You re supposed to be working closely with this guy, and you don t find out till much later that he s actually the one behind it all. And that highlights one of the most important aspects of adventure and text games for me the turnaround point.江城：じゃあ‥‥一緒に行動する刑事が犯人という、ものすごい結末なんです。彼とずっと一緒に行動していくんですが、最後の最後にならないと真相はわかりません。テキストアドベンチャーゲームにおいて最も重要なことのひとつ、転換点を私に見せてくれたのです。In the Ace Attorney series you always have these surprising twists, sometimes two or three times in one case. You just never know what to expect. That s what keeps adventure games interesting for me.逆転シリーズにおいては、1つの事件の中で、2つや3つのこういった驚くべき逆転劇を見ることになります。そしてあなたは何が起こるか全く解らない。それが私にとって、アドベンチャーゲームの面白さです。1UP It s obviously a very different type of game, but another popular adventure game I m sure you ve spent some time with is Professor Layton.1UP：明らかに異なるタイプのゲームですが、もうひとつの有名なアドベンチャーゲームとしてレイトン教授があります。ME Yeah, I played the very first one. And, you re probably aware that the puzzles themselves are based on a much older book series in Japan called Mental Gymnastics. I never found just doing the puzzles themselves all that engaging, but I m just amazed that they were able to fit them into this story and make it interesting. It s good that it brings these types of puzzles to a wider audience.江城：ええ、第1作目はプレイしました。そして、パズル自体は思考型パズルと日本で呼ばれているものに似ていることにおそらく気がついたでしょう。私はパズル自体にはさほど興味がありませんでしたが、それをストーリーにうまく組み込んで面白くしていることに驚きました。多くの人々にこの種のパズルを体験してもらうことは良いことです。1UP Obviously, he s in the title, so Miles Edgeworth is this game s central character. After bringing in a new protagonist for the previous game, Apollo Justice, what made you decide to bring back this character as opposed to using someone new?1UP：タイトル（Ace Attorney Investigations Miles Edgeworth）通り、御剣怜侍がこのゲームの主役であることは明白です。前作で新主人公（王泥喜）を登場させたのに、他のキャラクターに戻すことを決めたのは？ME Well, we wanted to make a new game with new skills like logic and deduction, things like that. But we took a look at the character rankings in Japan and, next to Phoenix Wright, the next most popular character was Edgeworth. He s really quite popular, and so we thought that made him a good choice as the central character for this game.江城：私たちは論理と推論に基づく新しいゲームを創りたかったのです。日本での人気キャラクターを見ると、成歩堂の次に最も人気があるのは御剣でした。彼は本当に人気があります。そのため、このゲームでは、彼を主役にするのが良いと考えました。1UP Was there anything you and the team wanted to do with the game that you just weren t able to, because of time constraints or other technical hurdles?1UP：時間的制約や、技術的な問題で、あなたや開発チームができなかったことは？ME Actually, one of the things that the director and I had talked about was the Little Thief system. We d wanted to add a lot more features -- to make a bit more in-depth. But we just ran out of time and weren t able to integrate it as fully as we d wanted to. It s little more simplistic than we d originally envisioned, but that was just a problem with time.江城：実は、ディレクターと私が話し合っていたものの1つに、「ちょっとした泥棒システム」がありました。私たちはもっと多くの特徴を加えたかったのです――徹底的に。しかし、開発期間の問題で、完全にそれらを作ることができませんでした。元々私たちが想像していたものより多少安易ではありませんが、結局は時間の問題でした。1UP Is there anything you feel you ve learned from Ace Attorney Investigations that you ve been able to apply to your current project, Okamiden?1UP：逆転検事から学んだことが、あなたの今のプロジェクトである大神伝に生かされていますか？ME Well, I m also the producer on Okamiden, so the role itself is very similar. Ace Attorney was my first solo job as a producer, so a lot about learning games promotion, the timing of releasing information, keeping players interested. Various things like that about how to promote a game.江城：大神伝ではまたプロデューサーなので、役割そのものはとても似ています。逆転裁判は私の最初のソロでのプロデューサー活動で、ゲームのプロモーション、発売情報のタイミング、プレイヤーに興味をもってもらうことなど、様々なことを学びました。But a real learning moment came when we put together the first build of Investigations. We went around showing the game to the company, and we actually got a lot of negative reactions. So, we had to go back to the drawing board and do a lot of rethinking, redesigning, reconceptualizing.しかし、捜査方法の最初の構築をした時が、本当に学べた瞬間でした。私たちが会社にゲームを見せても、ネガティブな反応ばかりでした。私たちは制作に戻らなければならず、再考し、設計し直し、コンセプトを見直さなければなりませんでした。Talking with the director, we had to think about who Edgeworth is as a character. We realized that he s actually very logical. Originally the game was simply about visiting crime scenes and investigating, but when we instituted the Logic mechanic, that changed how the game plays completely.ディレクターと、御剣というキャラについて話し合いました。私たちは、彼が非常に論理的であると考えました。当初、ゲームは単に犯行現場を訪れ、調査するだけでした。しかし、ロジックシステムを考え出した時、ゲームの方向性は変わりました。1UP Did you ever consider brining the series over to another platform besides DS?1UP：シリーズをDS以外で発売することについては？ME From the beginning, we knew this would be a DS game. The previous games were all on DS, and there s just a natural flow to continue with DS. We never really considered trying it on any other system.江城：最初から、DSのゲームを創ることを考えていました。前作までは全てDSだったので、それが自然な流れでした。私たちは他のハードでの発売を全く考えませんでした。1UP Have you felt limited at all by the DS? With Nintendo iterating on its handheld so frequently, is there any functionality that you wish it would add to the system that you think would be great to use in a game?1UP：DSによって制限されることはありませんでしたか？ 任天堂はしばしば携帯ゲーム機を出していますが、ゲームに使うためのシステムを加えて欲しいと思うことは？ME I m really not the type of person to think, Oh, I wish they had this, I wish they had that. I look at it realistically, I look at the specs. Then I think, What can we do with this? What kind of fun game can we create to take advantage of this machine the most? 江城：私は「これがあればいいのに、あれがあればいいのに」というタイプではありません。スペックを見て、考えます。「これをどうできるだろうか？ このハードでどんな楽しいゲームを作れるだろうか？」I guess it goes back to my roots as a programmer, but I really would just want the system to have more memory, maybe a better video card. Stuff like that. Something so we can make the best looking game possible. It s not the most wishful thinking perhaps, but that s the way I look at it.私は、それがプログラマーとしての私のルーツに戻ると思います。ただ、より多くの容量、良いビデオカードがあれば良いとは思います。より良いものを作るために。1UP Going back to your roots, you ve held so many different positions in the industry, are there any moments in particular that stand out for you? What roles did you most enjoy?1UP：ゲーム業界で色々と異なるポジションを体験してきて、特に卓越していることは？ どんな仕事が楽しかったですか？ME Starting out as a programmer for Capcom, it really was fun to be able to realize a planner s vision. A planner would come up to me and say, Here are the game s rules, or, Here are the designs. And it would be up to me to put it together and make it appear on the screen. That was really great, to immediately see these ideas take fruit and know that you re the one who brought these ideas to life.江城：カプコンではプログラマーとしてスタートして、それにはプランナーとしての展望を認識できる楽しさがありました。プランナーは「これがゲームのルールだ」とか、「これがデザインだ」と言ってきます。それらをまとめるのは私次第で、ディスプレイに映し出すことができます。それは面白いことでした。As a director, it s tough to be head of a team because you then take on responsibility for everything that the team does and all the decisions. If you decide to take the game in one direction instead of another, you have to live with those consequences. It s heavy and hard, but it s also good because you have a lot more influence over the game; you can put in things you want to put in. Of course it s not 100% about what you want. It s also about listening to the ideas and opinions of your team and being able to take all those ideas and make it into one solid game. Having everything come together, the realization of those things makes it all worth it.ディレクターとしては、チームの全ての責任と決定を引き受けるので、大変なことです。もしゲームの方向性を変えるなら、その結果に耐えなくてはなりません。それは重く、厳しいです。しかし、それはまた、ゲームに良い影響を与えることにもなります。もちろん、期待していたことの100％がかなうわけではないのですが。それはまた、チームの考えや意見を聞いて、決定し、ひとつの凄いゲームが出来ることでもあります。これらの実現は素晴らしい価値があります。Being a producer is a double-edged sword. It s hard, but it s a very enjoyable at the same time. You get to stand in a different position from the director, and you get to watch a game grow from the first drafts to the very end. It s interesting to be able to manage and oversee everything in that respect. And being able to promote the game, getting out to the various media outlets is a lot of fun too. Learning how to excite people about your particular title. It s trying, but very compelling at the same time.プロデューサーであることは、諸刃の剣です。大変でもあり、楽しくもあります。ディレクターとは異なる立ち位置になり、ゲームが最初の草案から、完成まで成長していくのを見ていくことになります。その点で、全てを管理し、監督していくことは面白いです。そして、ゲームの広告や、色々なメディアに出演することは、楽しみでもあります。自分の作っているものを人々に喜んでもらう方法を学ぶこと。それは挑戦的で、同時に魅力的でもあります。1UP I know you don t control marketing in America directly, but the Ace Attorney series in particular has always had wonderful pre-order bonueses for Japan in the past. But when those same games come Stateside, it s usually without as much fanfare and with just the standalone software. Since you ve been working on the past few titles directly, how do you think the company s approach has changed with each title?1UP：私はあなたがアメリカで直接販売管理をしないということは知っていますが、逆転シリーズは過去、日本で素晴らしい予約特典がありました。しかしアメリカではそれがありません。過去直接少しのタイトルに関わり、あなたは、会社がどのように各ゲームの広告方法を変更したのだと思いますか？ME We ve definitely made some changes in how we promote things overseas versus in Japan. For example, in Japan we focus mainly on interviews with the regular press outlets like Famitsu. But in the West, we ve found going directly to the community has been very important. For Ace Attorney, we recently did a live Q A over the Capcom UStream page. It s something that s always changing, and we definitely don t have the perfect formula right now, but we re always listening to the community.江城：確かに、私たちが日本で発売したものを海外で宣伝する場合、多少方法が変わりました。例えば、日本では、宣伝するには私たちはファミ通のようなプレスの発表で、主にインタビューに集中しています。しかし海外では、私たちは、直接コミュニティで呼びかけることが重要であることがわかりました。逆転シリーズのために、私たちはカプコンのUStreamでQ Aをライブで行いました。常に色々なことが変化しています。今私たちは完全な方法というものを持ちませんが、常にコミュニティを開いています。1UP Do you think there are any particular differences between fans of the Ace Attorney series in the East and the West?1UP：日本と海外では、ファンに違いがあると思いますか？ME Actually, I went to ComicCon last year, and it was really great to see so many of our American fans in person. I don t think there s a difference between the two, or between any other countries in that respect; everyone who enjoys the games seems to enjoy them for the same reasons.江城：去年ComicConに行って、直接アメリカのファンに会えたことは、とても素晴らしいことでした。私は、国の間で違いがあるとは思いません。誰もが、同じ理由でゲームを楽しんでいるのです。1UP Well, thank you so much for taking the time to come out and talk with us. We know a lot of fans out there are eagerly awaiting the next game s release later this month.1UP：ありがとうございました。海外ファンは、今月の発売を熱心に待っています。ME Thank you very much.江城：ありがとう。 ▲ページ上へ▲
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- PR TIMES まるで別人！一人二役を見事に演じたイ・テギョンさん【インタビュー】映画『湖底の空』 - 映画ログプラス 「どんぐり共和国」から生まれたブランド「Donguri Closet」新商品、キキやシータ、アリエッティをイメージしたゆったりくつろげるリラックスウェア4種が2021年6月26日（土）発売！ - PR TIMES コロナ禍の新業態！オンライン教育サービスで全国の子どもたちの成績アップに貢献 “先生が教える”オンライン個別指導塾「そら塾」、本格的に提供開始 - PR TIMES テラ・ラボ 、「Japan Drone 2021」出展。「TERRA LABO Fukushima」や新機体を初披露 - DRONE 『湖底の空』公開記念 佐藤智也監督作品 一挙配信決定！！ - 映画ログプラス 『すみれの空』レビュー：美しくておだやかなのに、“友達のお花”をはじめすべてが不穏なアドベンチャー - IGN JAPAN 「10億部突破（してほしい）」――借りた本を自作の帯で絶賛し返却 本を貸し借りしたくなる試みが話題（1/2 ページ） - - ねとらぼ スタジオジブリ作品グッズショップ「どんぐり共和国」 ちょっとレトロで色とりどりのトトロたちが大集合！「イロイロトトロ」シリーズが2021年6月上旬より発売 - PR TIMES 経営体制強化のため、COOとして石亀一郎氏、グロービス・キャピタル・パートナーズより社外取締役 磯田将太氏、顧問 仮屋薗聡一氏が就任 - PR TIMES 普段は会社勤めの二刀流グラドル・成海 空「この撮影のために腸活でウエストを６ｃｍ落としました」 - ニコニコニュース 唐揚げに合う「万能たれ」、大湊Sora空っ！1日発売 - 朝日新聞デジタル 09 星野村 福岡県｜棚田と茶畑と星が広がる里｜SATO〜次世代に残したい里〜：朝日新聞デジタル - 朝日新聞デジタル 「スタジオ地図」10周年、細田守監督最新作『竜とそばかすの姫』公開記念 宇宙ミュージアムTeNQ（テンキュー）にて『スタジオ地図の宙（ソラ）と雲展』開催決定！ - PR TIMES “絶対に行きたい信州の絶景”をお得に楽しめるスペシャルチケットが誕生！ - 地球の歩き方ニュース＆レポート 【東道後のそらともり】愛媛初！セルフロウリュを導入したサウナ室が2021年6月1日リニューアル - PR TIMES ukka 公式ブログ - asmr（茜空） - Powered by LINE - lineblog.me 色鮮やかで絵本のようなタッチのアドベンチャーゲーム『すみれの空』がSwitch/PCで5月27日に発売決定 - IGN JAPAN 株式会社空、データドリブン経営を担う人材育成プログラムを提供 ～第一弾として、近畿日本鉄道のDXを支援～ - PR TIMES 日中韓合作映画『湖底の空』予告編公開 清水崇、向井康介らのコメント到着 - CINRA.NET（シンラドットネット） 重症児デイサービス 上越に初開設 医療的ケアを支援 - 新潟日報 重症児放課後デイサービス「Sora」 5月1日に開設 | ニュース - joetsu.ne.jp 全日空商事、ショッピングサイト「SorANAka」をグランドオープン - TRAICY（トライシー） みなさんはじめまして！ 14歳 廣瀬 奏空(そら)です☺︎ Shibu3 project 公式ブログ - lineblog.me キャラアニはPS Vita専用ソフト「英雄伝説 空の軌跡 Evolution」三部作「英雄伝説 零の軌跡 Evolution」「英雄伝説 碧の軌跡 Evolution」をお求めやすい価格にしました。 - PR TIMES 友成空『18』往年のシティ・ポップ的煌めきとイマっぽさを同時に纏ったニューカマーの登場 - Mikiki 友成空の人生初インタビュー、王道を歩む18歳のシンガーソングライターがデビュー作への思いを語る - 音楽ナタリー 特集・インタビュー - 音楽ナタリー 日本製ジオデシックドームメーカーが作る多様性ドーム [宙のドーム] SORA no DOME - PR TIMES スタジオジブリ作品オンライングッズショップ「 どんぐり共和国 そらのうえ店」にて『紅の豚』のポルコが乗るサボイアがki-gu-miで登場！2021年3月24日（水）10時より発売 - PR TIMES 北野クラブソラで桜の通り抜け 神戸市中央区 - KissPRESS 現役高校生SSW友成空、デビュー作から先行配信曲のMV公開（動画あり） - ナタリー 【空 音央】オススメは『しとやかな獣』と『わが町』川島雄三──みんなで語ろう!「わが日本映画」 - GQ JAPAN トロピカル〜ジュ！プリキュアにて先生になったよ！ の巻 徳井青空 そらまる 公式ブログ - lineblog.me 謎というそこはかとない不安が漂うアドベンチャー『すみれの空』体験版プレビュー - IGN JAPAN 【上尾市】イオンモール上尾に蓮田市で人気のお洒落な蕎麦ダイニング空楽がオープンします！オープンはいつ？ - 号外NET 上尾市・桶川市 スケートボード界のライジングスター・白井空良が ”Blind skateboards”から1st Pro Modelをリリース！ (2021年2月8日) - エキサイトニュース モスクワで空飛ぶタクシーが試験中（写真＋動画特集） - ロシアNOW とやま×私×フォト「家族増えたらまた来ようねー」そらねこ724（富山市）｜北日本新聞ウェブ[webun ウェブン] - webun.jp 名張の母娘チームが世界3位 DJ国際大会「IDA WORLD」 | 【伊賀タウン情報 YOU】 - ＹＯＵ ドローンで「空の道」作り農業・農村を活性化 （株）トルビズオン 増本衛ＣＥＯ【ＪＡアクセラレーターがめざすこと】 - 農業協同組合新聞 株式会社トルビズオン、多久市・多久市まちづくり協議会等とソラシェアを活用した上空シェアリングおよびドローン配送の実証実験を実施 - PR TIMES ときのそら2ndライブ「パラレルタイム」開催＆2ndアルバム発売日決定 - Mogura VR 広島空港北側「八天堂ビレッジ」に新たに「空の駅オーチャード」がオープン 2020年10月31日（土）オープニングイベントを開催 - PR TIMES 感染対策を演出に変える「サイレントフェス ＃ソーシャルディスダンシング」横浜夜景を見渡す屋上で開催決定！ - PR TIMES 東京オリンピック金メダル候補の白井空良が、神奈川県寒川町に屋内型スケートボードパークを建設するプロジェクトを始動！ - FINEPLAY 【ライブレポート】sora tob sakanaが6年の歴史に幕、4時間超えライブで50曲出し尽くし煙の中へ（写真14枚） - ナタリー sora tob sakana | Skream! 特集 邦楽ロック・洋楽ロック ポータルサイト - Skream! 上空シェアリングサービス「sora share(ソラシェア)」を提供する株式会社トルビズオンが、神戸市六甲山地区にてドローン配送実用化に向けた実証実験を実施 - PR TIMES そら散歩いわて - 岩手日報 スタジオジブリ作品グッズがそろうオンラインショップ「どんぐり共和国そらのうえ店」に大人向けスタジオジブリグッズをセレクトする「Donguri Closet(どんぐりクローゼット)」が期間限定で初登場！ - PR TIMES 超人気AV女優｢蒼井そら｣が明らかにした反日中国人の意外な本音 結局､靖国問題はどうでもいい - PRESIDENT Online 上空シェアリングサービス「sora share(ソラシェア)」を提供するトルビズオン、電通九州によるマーケティング支援が決定 - PR TIMES 空中権取引のsora shareがサッポロ不動産開発のピッチコンテストにてグランプリを獲得 - PR TIMES sora shareを運営するトルビズオン、「Be Smart KOBE」事業実施候補者に選定 - PR TIMES 「sora share(ソラシェア)」を運営するトルビズオン、つくばSociety 5.0社会実装トライアル支援事業に採択 - PR TIMES ホテルの料金設定支援サービス「MagicPrice」提供の空、GCPから資金調達——合計約4.7億円調達でシリーズAをクローズ、経営体制も強化 - THE BRIDGE,Inc. / 株式会社THE BRIDGE トルビズオン、JForestグループ組合林業と私有林上空における「空の道」設計を下関市で実施 - DRONE 上空シェアリングサービス「sora share(ソラシェア)」を提供するトルビズオン、JForestグループの組合林業と、全国初となる私有林上空における「空の道」の設計を下関市にて実施 - PR TIMES 「空に道をつくる」上空シェアリングサービス“sora share”を運営するトルビズオン、Kipsより総額2500万円の資金調達を発表 - PR TIMES 蒼井そら「消せない」けど作品販売停止にした理由は - 芸能 - 日刊スポーツ スタジオジブリ作品グッズを扱う「どんぐり共和国」オンラインショップ『そらのうえ店』がリニューアルオープン！3月5日(火)より先着でオリジナルトートバックをプレゼント - PR TIMES 驚きしかない…!ドラマチックな空写真が誰でも撮れちゃうコツ3つ｜スマホ撮影テク #29 - ananweb 空 ～SORA～とは 空 ～SORA～の45%は犠牲で出来ています。空 ～SORA～の27%は黒インクで出来ています。空 ～SORA～の17%は苦労で出来ています。空 ～SORA～の9%はマイナスイオンで出来ています。空 ～SORA～の2%はやらしさで出来ています。 空 ～SORA～＠ウィキペディア 空 ～SORA～ Amazon.co.jp ウィジェット 掲示板 名前（ＨＮ） カキコミ すべてのコメントを見る ページ先頭へ 空 ～SORA～ このページについて このページは空 ～SORA～のインターネット上の情報を集めたリンク集のようなものです。ブックマークしておけば、日々更新される空 ～SORA～に関連する最新情報にアクセスすることができます。 情報収集はプログラムで行っているため、名前が同じであるが異なるカテゴリーの情報が掲載される場合があります。ご了承ください。 リンク先の内容を保証するものではありません。ご自身の責任でクリックしてください。
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Outer Torso P-Z ※女性ものは参照程度に掲載しているので、ワンカットのみ掲載ですべて同じトリミングとしています。男女とも似た感じのデザインのものは女性のアイコン画を省略。 PEACH SYN-THREAD CROP SWEATER PHOENIX FORMAL DRESS WITH MICROARMOR LAYER POLICE BALLISTIC VEST POLKA DOT TRENCH COAT PUNCTURE-RESISTANT LINING POLYAMIDE JUMPSUIT POLYAMIDE-BLEND JUMPSUIT WITH MICROMESH POLYAMIDE-HOODED DUOLAYER BOMBER POLYAMIDE-BLEND SUIT JACKET POLYAMIDE-LINED ROCKER JUMPSUIT POLYCARBONATE NANOWEAVE TECHIE HARNESS POLYCARBONATE WESTERN FRINGE VEST POWDER PINK LIGHT POLYAMIDE BLAZER POWDER PINK TRIVANADIUM ALLOY BALLISTIC VEST PRACTICAL PLAID SHIRT WITH MICROMESH PREDATOR ARAMID ARMOR (FROM ROGUE) PRIMEVAL FLAME ROCKERJACK PUNCTURE-RESISTANT LONG COAT PUNK ARAMID VEST PUNK BOOSTWEAVE BIKER JACKET PUNK HIGH-COLLAR VEST PUNK SHORT-SLEEVE DUAL-MEMBRANE JACKET PUNK SHORT-SLEEVE POLYCARBONATE SPIKED JACKET PUNK ULTRAWEAVE FLIGHT JACKET PURPLE FORCE TACTICAL JUMPSUIT PURPLE SYMPHONY ENHANCED POLYAMIDE EDGERUNNER RED DRAGON COCKTAIL JACKET WITH TITANIUM MICROPLATE LINING REFLECTIVE METALWEAVE NYLON VEST REINFORCED SHORT PUFFER REINFORCED SYNLEATHER NOMAD JACKET REINFORCED-LAMINATE MILITARY FLIGHT JACKET REPLICA OF JOHNNY S SAMURAI JACKET ROCKER S HEART CRYSTALJOCK BOMBER ROCKERJACK WITH ANTI-PUNCTURE MESH ROSA ESCARLATA EMBOSSED ARMOLEATHER BIKER VEST ROSA PLATINO REINFORCED ROCKERJACK ROZOVAYA REKA PENCIL DRESS WITH PROTECTIVE MEMBRANE SAEKO S PROTOTYPE TACTICAL ARAMID BREASTPLATE SALAMANDER EAZY-BREATHE TARP-WEAVE JACKET SALOON STYLE ULTRA-DURABLE DRESS SHIRT SAPFIR 3D HEAVY TRIPLE-WEAVE NANOCARBON POZER-JACKET SCALED KINRYU BLAZER WITH CARBON-COMPOSITE INSETS SCAV BALLISTIC VEST SCAV PLASTIC WINDBREAKER SCHWARZE LIMETTE ARAMID-FABRIC DRESS SECOND CONFLICT BIKER JACKET SECOND CONFLICT CUTOUT BODYSUIT SECOND CONFLICT FLIGHT JACKET SECONDHAND SYNTHLEATHER VEST SEMURAI CYRSTALJOCK BOMBER SHABBY 6TH STREET ARAMID VEST SHABBY HOODED CUT-OFF SHIROKURO HIGH-COLLAR COMPOSITE-LINED VEST SHORT PUFFER WITH MICROPLATE UNDERLAYER SILBER IRBIS BOLERO GMO-WEAVE BOMBER SILVEROCK BULLETPROOF-LAMINATE BIKER VEST SIMPLE BOLERO RUBBER-COATED BOMBER SLEEVELESS ARMOR-PLATED FIELD JACKET SMILEY HARD PROTECTION-LAYERED BOMBER SOVIET MOSCOW DREAM ANTI-SHRAPNEL BOMBER SPIKED MAELSTROM SHORT-SLEEVE JACKET SPOTTED ARMOR-COATED CORPO-SKIRT SPUNKY MONKEY ARAMID COAT STAINED PUNCTURE-RESISTANT COAT STREAM EXTREME HIGH-PERFORMANCE JUMPSUIT STREETART HOODED BOMBER STUDDED BIKER VEST STURDY SHOULDER STRAPS STURDY SYNFABRIC SUIT JACKET WITH POCKET SQURE STURDY SYNLEATHER BOLERO BOMBER STYLISH TEN70 DAEMON HUNTER COAT STYLISH TORA TO RYU COAT WITH TITANIUM INSERTS SYNCOTTON COCKTAIL JACKET SYNLEATHER CARBON-COLLAR POZER-JACKET SYNTHETIC CORPORATE JACKET SYNWEAVE ARMOR-COATED YUKATA SYNWEAVE ARMOR-LAYERED PSYCHO BOMBER TAMASHI ENHANCED SHORT PUFFER TAMASHI STRETCH-LAMINATE RALLY BOLERO TEN70 GRAFFITI JUMPSUIT TEN70 SLEEVELESS FIELD JACKET TENKA MUSO COMBAT MOTORCYCLE JACKET THERMO-QUILTED CUTOUT BODYSUIT THERMOSET MILITARY FIELD JACKET THICK DOUBLE KNIT EVENING JACKET TIMEWORN TRENCH COAT TORERA REAL ULTRAREACTIVE LAMINATED POZER-JACKET TORIKKUSUTA ARAMID-WEAVE CRYSTALJOCK BOMBER TRAUMA TEAM ARMOR-WEAVE TACTICAL VEST TRILAYER ARAMID-WEAVE FIXER COAT / TRILAYER ARAMID-WEAVE FIXER SKIRT WITH JACKET TYGER CLAWS CERAMIC-LAMINATE ARAMID COLLAR TYGER CLAWS REINFORCED EDGERUNNER TYGER CLAWS REINFORCED TACTICAL HARNESS ULTIMATE PUNCH FIELD-GENERATING PROTECTIVE POZER-JACKET ULTRALIGHT COMPOSITE VEST ULTRALIGHT SHINE SPECTRUM TRENCH COAT URBAN JUNGLE HIGH-COLLAR REINFORCED LEATHER VEST V S OFFICE BLAZER V S VEST (WITH BAKKERS PATCH) V S VEST (WITHOUT BAKKERS PATCH) VALENTINO S DUAL-WEAVE EDGERUNNER VALENTINOS ARMOR-PLATED THERMOSET ARAMID COLLAR VALENTINOS COMPOSITE-COLLAR SUEDE POZER-JACKET VALENTINOS LEATHER SHOULDER STRAPS VICTORIAN ROSE ANTI-SHRAPNEL PENCIL DRESS VIRTUGLOW COMPOSITE BALLISTIC VEST VOODOO BOYS ANTI-INTERFERENCE NETRUNNER JACKET WAKAI UMI FLAME-RESISTANT YUKATA WARM NANOWEAVE COTTON SHIRT WASP ANTI-PUNCTURE POLYAMIDE PUFFER VEST WELL-WORN 6TH STREET EDGERUNNER WOLF SCHOOL JACKET WOOL SUIT JACKET WITH REINFORCED SYNFIBER-WEAVE WORN PUNK COAT WORN SCAV FIELD JACKET WORN-OUT BALLISTIC VEST WOUNDED MACHINE DUOLAYER COMBAT FLIGHT JACKET WRAITHS COAT WITH IMPROVISED BULLETPROOF LINING WRAITHS DUAL-REINFORCED SHOULDER STRAPS WRAITHS HEAVY IMPACT-ABSORBING MOTORCYCLE JACKET WRAITHS RALLY BOLERO JACKET WRAITHS TRILAYER EDGERUNNER XX PUNCH! ARMOR-COATED HOODED BOMBER YELLOW COBRA CARBON-REINFORCED RACING SUIT YUNAMI FORMAL HYBRID DUOWEAVE JACKET ZOLOTOY ULEY SOVIET-STYLE FIREPROOF WINDBREAKER ▲TOPへ戻る
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目次 ↑ 概要 URL インストール PortableAppscom Platform向けに用意されている主なポータブルアプリケーション 設定 Tips タグ 概要 各種アプリケーションの実行形式と設定ファイルやユーザデータをセットにした動作環境一式をUSBメモリなどで持ち運ぶためのプラットフォーム 動作させるPCのレジストリに依存しない、痕跡を残さない 設定ファイル等が相対パスで定義される PortableApps.com Platformで動作するようにパッケージングし直された各種ソフトのポータブル版が用意されている 英語版が主だが、exeファイルやlngファイルを入れ替えるだけで日本語化可能なものもある 「アプリケーション仮想化」の一種であり、インストール先はUSBメモリに限らない： オンラインストレージ （ネットカフェなどでも自分の環境が使える） オンラインストレージを使う場合は、TrueCryptなどで暗号化をすること LAN内のファイルサーバ （LAN内の別のクライアントPCでも共通の環境が使える） ローカルのハードディスクドライブ （アプリ設定情報の管理・バックアップが簡単になる） 2009年のSourceForge Community Choice Awardsの4部門で受賞獲得 http //sourceforge.net/community/cca09/winners/ URL http //portableapps.com/ インストール ポータブル版の各種ソフトをインストールするには、 ランチャメニューの オプション(O) より多くのアプリケーションの取得(G) を使ってサイトからインストーラパッケージ(paf形式)をダウンロードする ランチャメニューの オプション(O) 新しいアプリケーションのインストール(I) を使って、ダウンロードしたpaf形式ファイルを選択する USBメモリの定められた特定のフォルダに配置される インストール例 PortableAppscom Platform向けに用意されている主なポータブルアプリケーション 7-Zip Command Prompt Portable CoolPlayer+[作成] Eraser Foxit Reader FreeCommander Google Chrome InfraRecorder KeePass Mozilla Firefox Mozilla Thunderbird MPlayer[作成] Notepad++ OpenOffice.org[作成] PortableFileAssociator PuTTY Songbird SpeedCrunch Synkron VLC Media Player[作成] VVV WinDirStat WinMerge WinSCP 設定 ランチャメニュー ＞ オプション(O) 小さいフォント(S) 言語(A) Japanese Tips PortableApps.comをインストールするUSBメモリのフォーマットとしては、FATもしくはFAT32を使うこと。 NTFSを使用すると「所有者」情報もファイルシステムに記録されアクセス制限の対象になるため、ユーザアカウントの同期ができていない接続先のPCからは書き込み動作でエラーになる。 PortableApps.com Platform 自身には明示的なプロキシ設定がない 「設定を自動的に検出する(A)」オプションをONにしておくこと そうしないと、PortableApps.com Platform Updater がプロキシの検出に失敗することがある タグ @会社 @自宅 モバイル
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TOXICOLOGICAL PROFILE FOR WHITE PHOSPHORUS -index ▼2 HEALTH EFFECTS ▼▼2.2 DISCUSSION OF HEALTH EFFECTS BY ROUTE OF EXPOSURE 2.2.2 Oral Exposure -2 2.2.2 Oral Exposure(2.2.2.0 preface) 2.2.2.1 Death 2.2.2 Oral Exposure -22.2.2.2 Systemic Effects(preface) Respiratory Effects. Cardiovascular Effects. Gastrointestinal Effects. Hematological Effects. Musculoskeletal Effects. Hepatic Effects. Renal Effects. Dermal Effects. Other Systemic Effects. 2.2.2 Oral Exposure -32.2.2.3 Immunological and Lymphoreticular Effects 2.2.2.4 Neurological Effects 2.2.2.5 Reproductive Effects 2.2.2.6 Developmental Effects 2.2.2.7 Genotoxic Effects 2.2.2.8 Cancer 2.2.2.2 Systemic Effects (preface) Systemic effects of white phosphorus in humans and animals after oral exposure are discussed below. The highest NOAEL value and all reliable LOAEL values from each reliable study for systemic effects in each species and duration category are recorded in Table 2-2 and plotted in Figure 2-2. No studies were located regarding ocular effects in humans or animals after oral exposure to white phosphorus. Respiratory Effects. Studies on respiratory effects following acute oral exposure of humans to white phosphorus were limited to case reports of intentional or accidental consumption of materials containing white phosphorus. Although intake of phosphorus was often reported, dose could be estimated for only one study (Hann and Veale 1910), because vomiting and/or gastric lavage nearly always occurred soon after poisoning, expelling much of the ingested phosphorus from the body. Tachypnea (increased respiratory rate; 48 breaths/minute) was observed in a woman consuming rat poison containing 4% white phosphorus (Hann and Veale 1910); the woman apparently did not vomit until the second day, and the vomitus was clear. The estimated dose was 2 mg/kg. Four days after ingesting the rat poison, the woman died, apparently from liver failure. Autopsy showed that the pleural cavity was filled with a dark fluid, but no histological abnormalities were observed in the lungs (Hann and Veale 1910). In the following studies, no doses could be estimated for respiratory effects because of vomiting and/or gastric lavage. In a case report involving ingestion of rat poison containing white phosphorus, the patient arrived at a hospital in a coma and displayed Cheyne-Stokes respirations and rales (Wechsler and Wechsler 1951). The Cheyne-Stokes respirations increased to an extreme degree, and the patient died. Autopsy revealed pulmonary congestion and edema throughout the stroma. Increased respiratory rate (56 breaths/minute) and rales also were observed in an infant ingesting rat poison containing white phosphorus (Rao and Brown 1974). The child died, and autopsy revealed evidence of pulmonary edema. Rales were observed in a child ingesting a fatal dose of white phosphorus in fireworks; autopsy indicated that the lungs were normal except for some fibrous adhesions (Dwyer and Helwig 1925). Hemorrhagic bronchopneumonia was observed following autopsy of a man ingesting a fatal dose of rat poison containing white phosphorus (Winek et al. 1973). Autopsy of a child who died following ingestion of a firecracker revealed fatty deposition in parenchyma, bronchial epithelium, and tracheal epithelium and cartilage (Humphreys and Halpert 1931). Death from cardiopulmonary failure was reported for a 63-year-old woman (Winek et al. 1973), a 2-year-old boy (Simon and Pickering 1976), and a 3-year-old girl (Simon and Pickering 1976) following ingestion of white phosphorus in rat poison; a respiratory rate of 44 breaths/minute was initially observed in the girl (Simon and Pickering 1976). Increased respiratory rate was observed prior to death in two case reports involving ingestion of rat poison (Talley et al. 1972; Winek et al. 1973). Shallow respirations and cyanosis were observed prior to death in an adult female following ingestion of rat/roach poison containing white phosphorus (Rubitsky and Myerson 1949). Rales were observed 1 day after intentional ingestion of rat poison by a 30-year-old man; 2 days later the patient went into shock but survived the poisoning and eventually recovered (Pietras et al. 1968). No treatment-related respiratory effects were reported in children treated with white phosphorus for intermediate durations. No treatment-related microscopic changes were observed in the lungs of rats exposed to 0.2 mg/kg/day white phosphorus in the diet for a chronic duration (Fleming et al. 1942) or 0.075 mg/kg/day phosphorus by gavage for an intermediate duration (LRDC 1985). Heavy breathing and apnea were reported following ingestion of a fatal quantity of white phosphorus by a cat (Frye and Cucuell969). Necropsy revealed hyperemia, hemorrhage and edema in the lungs. Cardiovascular Effects. Alterations in electrocardiograms, such as altered or inverted T waves and changes in the QRS complex, and other cardiac changes, such as tachycardia, arrhythmias, atrial fibrillation, and decreased ventricular contractility, have been observed in individuals accidentally or intentionally ingesting a single dose of white phosphorus (Dathe and Nathan 1946; Diaz-Rivera et al. 1950, 1961; Dwyer and Helwig 1925; Ehrentheil 1957; Matsumoto et al. 1972; McCarron et al. 1981; Newburger et al. 1948; Pietras et al. 1968; Rao and Brown 1974; Simon and Pickering 1976; Talley et al. 1972). Damage to the myocardium was verified by a number of cases in which histological examination of the heart was performed. Prominent cross striations in the myocardium (Dwyer and Helwig 1925), fatty infiltration of muscle (Diaz-Rivera et al. 1961; Humphreys and Halpert 1931; Wertham 1932), necrosis of myocardium (Wechsler and Wechsler 1951), markedly dilated cardiac chamber (Rao and Brown 1974), and interstitial edema of the myocardium and vacuolation of cells (Talley et al. 1972) have been observed. Because of vomiting and gastric lavage, doses cannot be calculated from the human studies. No cardiac effects were reported in longer term human studies. In addition to the effects on the heart, a number of vascular effects have been observed in humans acutely exposed to white phosphorus. A markedly decreased or undetectable blood pressure (Caley and Kellock 1955; Dathe and Nathan 1946; McCarron et al. 1981; Rubitsky and Myerson 1949; Simon and Pickering 1976; Wechsler and Wechsler 1951), vascular collapse (Diaz-Rivera et al. 1950, 1961), undetectable or decreased pulse (Dwyer and Helwig 1925; Rubitsky and Myerson 1949), and increased pulse (Dathe and Nathan 1946; Hann and Veale 1910; McCarron et al. 1981; Wechsler and Wechsler 1951) have been observed. In addition, individuals have died following cardiopulmonary arrest (Simon and Pickering 1976; Winek et al. 1973), which may be due to effects on the heart or vascular system. A dose of 2 mg/kg/day for vascular effects was identified from the Hann and Veale (1910) report of a woman ingesting a single dose of white phosphorus. Dose levels cannot be estimated for the other case reports. Hemorrhaging in internal organs, as well as the appearance of petechial hemorrhages on the skin, have been reported in a number of acute human exposure cases (Hann and Veale 1910; Humphreys and Halpert 1931; Winek et al. 1973). It is not known whether these effects are due to impairment of the integrity of the blood vessels or due to damage of the affected organ (e.g., liver, stomach) itself. In rats administered 0.075 mg/kg/day white phosphorus for an intermediate duration, no histological alterations were observed in the heart (Bio/dynamics 1991; IRDC 1985). In rats exposed for an intermediate duration to an unknown concentration of airborne white phosphorus from the furnace room of a phosphorus factory, an increase in permeability of capillary walls, lesions in the walls of blood vessels and evidence of impaired microcirculation were observed in the mouth (Ruzuddinov and Rys-Uly 1986). These effects probably resulted from the local action of white phosphorus on the oral cavity. Gastrointestinal Effects. Most of the human case reports listed vomiting as an early effect following ingestion of a single high dose of white phosphorus (Caley and Kellock 1955; Dathe and Nathan 1946; Diaz-Rivera et al. 1950; Dwyer and Helwig 1925; Ehrentheil 1957; Fletcher and Galambos 1963; Greenberger et al. 1964; Hann and Veale 1910; Humphreys and Halpert 193 1; Matsumoto et al. 1972; McCarron et al. 1981; McIntosh 1927; Newburger et al. 1948; Pietras et al. 1968; Rubitsky and Myerson 1949; Simon and Pickering 1976; Wechsler and Wechsler 1951; Winek et al. 1973). The doses that induced vomiting ranged from 2 to 23 mg/kg (Caley and Kellock 1955; Ehrentheil 1957; Fletcher and Galambos 1963; Harm and Veale 1910; Matsumoto et al. 1972; McCarron et al. 1981; Newburger et al. 1948; Rubitsky and Myerson 1949). Vomiting generally started within hours after ingesting the white phosphorus, and sometimes continued for many days. Other gastrointestinal effects included abdominal cramps or pain (often severe) (Dwyer and Helwig 1925; Ehrentheil1957; Fletcher and Galambos 1963; Greenberger et al. 1964; Humphreys and Halpert 1931; McCarron et al. 1981; Newburger et al. 1948; Pietras et al. 1968), vomiting blood and/or pieces of the gastric mucosa (Dathe and Nathan 1946; Diaz-Rivera et al. 1950; Rubitsky and Myerson 1949), necrosis and erosion of mucosa in the esophagus, stomach, duodenum, and jejunum (Wechsler and Wechsler 1951), and gastrointestinal hemorrhage (Dwyer and Helwig 1925; Hann and Veale 1910; Humphreys and Halpert 1931; Wertham 1932, Winek et al. 1973). These effects, with the exception of necrosis, were probably due to the irritating effects of white phosphorus on the mucosa of the gastrointestinal tract. Vomitus often contained white phosphorus, indicating that vomiting generally occurred before all white phosphorus and/or its oxidation products had been absorbed. No gastrointestinal effects were reported in children receiving treatment with 0.026-0.158 mg/kg/day white phosphorus for as much as 26 months (Phemister 1918; Compere 1930a). An infant became seriously ill during treatment with 0.083 mg/kg/day white phosphorus (6-month time-weighted average dose), but recovered entirely following discontinuation of the treatment (Sontag 1938). No vomiting or diarrhea was observed during the treatment period. Gastrointestinal effects were not reported in studies examining longer term occupational exposure to white phosphorus (Heimann 1946; Hughes et al. 1962; Kennon and Hallam 1944; Ward 1928). Erosion and hemorrhages in tissue in the esophagus and stomach were observed following ingestion of a fatal unknown quantity of white phosphorus by a cat (Frye and Cucuel 1969). Vomiting was observed in 6 of 21 dogs treated by gavage with an unknown quantity of white phosphorus from firecrackers (Dwyer and Helwig 1925). No gross or microscopic alterations were observed in the gastrointestinal tract of rats treated by gavage with 0.075 mg/kg/day for 204 days (IRDC 1985). Hematological Effects. Hematological effects have been reported in a number of case histories of individuals accidentally or intentionally ingesting a single dose of white phosphorus contained in rat (and cockroach) poisons or fireworks. Because most of the individuals vomited or received gastric lavage shortly after ingestion, the amount of white phosphorus available for absorption is not known. Increases in erythrocyte levels (Diaz-Rivera et al. 1950) and hemoglobin levels (Diaz-Rivera et al. 1950; McIntosh 1927); decreases in erythrocyte levels (Dwyer and Helwig 1925) and hemoglobin and/or hematocrit levels (Simon and Pickering 1973); and anemia (Caley and Kellock 1955) have been observed in some of these individuals. A number of individuals had no change in erythrocyte parameters (Ehrentheil 1957; Fletcher and Galambos 1963; Newburger et al. 1948; Simon and Pickering 1976). The decreases in erythrocyte parameters may be a reflection of the hemorrhages observed in specific tissues (e.g., gastrointestinal tract, liver, skin) (Dathe and Nathan 1946; Hann and Veale 1910; Humphreys and Halpert 1931; Wechsler and Wechsler 1951; Winek et al. 1973). In addition to these changes in erythrocyte parameters, changes in total or differential leukocyte levels were reported in a number of individuals acutely exposed to white phosphorus. Decreases in total leukocyte levels (Diaz-Rivera et al. 1950; Ehrentbeil 1957; Fletcher and Galambos 1963; McCarron et al. 1981; Newburger et al. 1948; Pietras et al. 1968) and decreases or increases in the percentage of polymorphonuclear leukocytes (neutrophils) have been reported (Ehrentheil 1957; McCarron et al. 1981; Pietras et al. 1968). No changes in leukocyte parameters were observed in a number of individuals (Fletcher and Galambos 1963; Newburger et al. 1948; Simon and Pickering 1976). Abnormally low protbrombin times or levels (hypo-prothrombinemia) and a moderate decrease in platelets were observed in a number of individuals ingesting single doses of white phosphorus (Caley and Kellock 1955; Dathe and Nathan 1946; Ehrentheil 1957; Fletcher and Galambos 1963; McCarron et al 1981). Most of the patients developed hypoprothrombinemia within 4-8 days (McCarron et al. 1981). This is probably secondary to the liver damage rather than a direct effect on platelets. No changes in hematological parameters were observed in a child ingesting phosphorized cod liver oil (0.083 mg/kg/day phosphorus) for 184 days (Sontag 1938). Anemia and leukopenia were observed in individuals occupationally exposed to white phosphorus chronically (Ward 1928). It is likely that workers were exposed by the inhalation, oral, and dermal routes. Because there is very little consistency regarding the length of time that elapsed between ingestion and measurement of hematological parameters and the doses cannot be calculated, it is difficult to compare the results of different studies. There is insufficient information to determine whether white phosphorus has a direct effect on erythrocytes and/or leukocytes. The effects observed may be secondary effects. The decrease in erythrocyte, hemoglobin, hematocrit and leukocyte levels may be secondary to hemorrhaging or hematoemesis (Diaz-Rivera et al. 1950; Rubitsky and Myerson 1949) and the increase in erythrocytes and hemoglobin may be a compensatory mechanism due to tissue anoxia. However, since red blood cell synthesis takes 3-5 days, the observed effects may be direct if they are occurring within l-2 days. A slight decrease in hemoglobin levels and increase in eosinophil levels were observed in a 30-year-old man who performed magic shows that involved placing white phosphorus pellets in the mucobuccal folds of his mouth for 15 years. He had no other personal habits that might adversely affect his health except for occasional bidi smoking for about 8 years (Jakhi et al. 1983). Information on hematological effects in animals is limited to one study in which a marked increase in total leukocyte levels and the percentage of monocytes were observed in a guinea pig acutely exposed to 0.9-2.4 mg/kg/day of white phosphorus in a complex dosing regimen (Lawrence and Huffman 1929). The study authors did not specify at which doses the effects occurred. Musculoskeletal Effects. Following ingestion of a fatal dose of rat poison containing white phosphorus by a woman, autopsy revealed fatty infiltration of essentially all tissues, including the musculature (Wertham 1932). Similar effects were reported following the death of a male child who accidentally ingested a firecracker containing white phosphorus; autopsy revealed fatty deposition in many tissues, included the diaphragmic muscle (Humphreys and Halpert 1931). Humans occupationally exposed to white phosphorus probably ingested some airborne white phosphorus. In a study of 71 humans occupationally exposed to white phosphorus, oral exposure to white phosphorus via hand-to-mouth activity was likely because the workers constantly handled a paste containing 4-6% white phosphorus and washroom facilities were inadequate (Ward 1928). In workers exposed to white phosphorus for intermediate durations, 2 of 44 developed phossy jaw, described as slight necrosis in the lower jaw. In workers exposed to white phosphorus for chronic durations, 12 of 27 developed phossy jaw, with necrosis ranging from slight to severe; 2 of the 12 workers developing phossy jaw died from complications related to the necrosis. The progression of the disease was similar in the cases described, usually beginning with the extraction of one or more teeth, poor healing of the socket, followed by necrosis of tissue in the jaw with severe pain and infection. Treatment consisted of repeated removal of destroyed bone tissue and teeth, draining of abscesses, and reconstructive surgery. In severe cases, extensive removal of necrotic bone tissue led to permanent disfigurement. However, exposure levels of white phosphorus were not reported (Ward 1928). Case reports of development of phossy jaw following intermediate or chronic occupational exposure to unreported levels of white phosphorus and phosphorus compounds describe a similar progression of symptoms, with similar results; even in cases of early diagnosis and prompt, intensive treatment of phossy jaw, recovery often took several years (Heimann 1946; Hughes et al. 1962; Kennon and Hallam 1944). It is likely that the effect of white phosphorus in the oral cavity is local, resulting from contact of “inhaled”white phosphorus particles with tissue in the mouth. White phosphorus may affect the oral mucosa. Dull, red spots in the oral mucosa, an early sign of phossy jaw, have been reported to precede its development in occupationally exposed workers (Kennon and Hallam 1944). The oral mucosa of workers exposed to white phosphorus has been described as having a dull, red, unhealthy appearance (Hughes et al. 1962). Exposed bones may be especially susceptible to the irritating affects of white phosphorus. It is not known whether white phosphorus ingested and absorbed into the systemic circulation contributed to the development of phossy jaw. Not all workers exposed to white phosphorus for longer-term durations developed phossy jaw. In a study of 71 workers exposed to airborne white phosphorus for intermediate or chronic durations, 4.5% and 44%, respectively, developed phossy jaw (Ward 1928). Forty-eight male workers with exposure to white phosphorus ranging from 1 to 17 years were found to be normal and healthy with regards to many parameters, including serum levels of calcium and phosphorus, and bone density; none of the men developed phossy jaw (Hughes et al. 1962). Tooth loss often precedes and accompanies the progression of development of phossy jaw (Heimann 1946; Hughes et al. 1962; Kennon and Hallam 1944; Ward 1928). Tooth loss during the later stages of phossy jaw clearly results from destruction of the-bone structure supporting the teeth (Heimann 1946; Hughes et al. 1962; Kennon and Hallam 1944; Legge 1920; Ward 1928). It is not known if tooth loss prior to diagnosis of phossy jaw or early in the development of the condition is related to the white phosphorus exposure. Poor dental hygiene alone can result in tooth loss, and in several case reports some of the workers were described as having poor dental hygiene (Kennon and Hallam 1944). Tooth loss followed by poor healing of the socket often precedes development of the necrosis (Heimann 1946; Hughes et al. 1962; Kennon and Hallam 1944; Ward 1928), suggesting that poor dental hygiene and exposure to white phosphorus may both be contributing factors to the development of phossy jaw. In a case report, five men developed “precursor signs” (delayed healing of extracted tooth sites and residual sepsis) of phossy jaw developed following tooth extraction and occupational exposure to white phosphorus (Hughes et al. 1962). However, the condition did not develop into “classical” phossy jaw. A man was repeatedly exposed to white phosphorus pellets, placed in the right mucobuccal cavity for magic shows, for . 15 years (Jakhi et al. 1983). After . 14.5 years of this type of exposure to white phosphorus, right maxillary molars became loose, and were subsequently lost. This was followed by a lack of healing and development of fistulae in the sockets of the right maxillary molars. White phosphorus necrosis of the jaw developed, with massive necrosis of the maxilla and floor of the antrum on the right side of the mouth; perforations were present through which the maxillary sinus and nasal cavity were visible. No effects were observed on the left side of the maxilla or on the mandible. Radiographs revealed no evidence of pathology in the chest and long bones. The damage to the jaw was probably caused by direct local contact of phosphorus with the soft tissue and bone in the oral cavity. No microscopic or histological abnormalities were observed in the bone of rats treated by gavage with 0.075 mg/kg/day for 204 days (IRDC 1985). Rats exposed for a chronic duration to 0.2 mg/kg/day white phosphorus in the diet had epiphyseal line thickening and greater extension of trabeculae into the diaphysis of unspecified bones, compared to a control group (Fleming et al. 1942). This study is limited by the failure to specify incidences of effects at interval during dosing and by the failure to state the dosing duration explicitly. Bone effects were observed in children (Compere 1930a; Phemister 1918; Sontag 1938) and young animals (Adams 1938a, 1938b; Adams and Sarnat 1940; Whalen et al. 1973) following acute and intermediate oral exposure to white phosphorus. Because white phosphorus-related effects were observed in growing bones, these effects were considered developmental effects, and are discussed in. Section 2.2.2.6. Hepatic Effects. Hepatic effects have been observed in most individuals accidentally or intentionally ingesting a single dose of white phosphorus. These effects include jaundice (Caley and Kellock 1955; Diaz-Rivera et al. 1950, 1961; Ehrentheil 1957; Greenberger et al. 1964; Humphreys and Halpert 1931; McCarron et al. 1981), hepatomegaly (Diaz-Rivera et al. 1950; Fletcher and Galambos 1963; Humphreys and Halpert 1931; Rao and Brown 1974; Simon and Pickering 1976; Wechsler and Wechsler 1951), increased levels of serum bilirubin (Caley and Kellock 1955; Fletcher and Galambos 1963; McCarron et al. 1981; Pietras et al. 1968), impaired liver function test results (Fletcher and Galambos 1963; Newburger et al. 1948; Pietras et al. 1968; Rubitsky and Myerson 1949), and increases in AST, ALT, and/or lactate dehydrogenase (Ehrentheil 1957; Matsumoto et al. 1972; McCarron et al. 1981; Pietras et al. 1968). In addition to these effects, autopsies or liver biopsies have revealed a number of histological alterations in these individuals. Necrosis (Fletcher and Galambos 1963; Rao and Brown 1974; Wechsler and Wechsler 1951), degeneration (Dwyer and Helwig 1925; Greenberger et al. 1964; Wechsler and Wechsler 1951), fibrosis (Greenberger et al. 1964), hemorrhages (Wechsler and Wechsler 1951), and fatty infiltration (Dwyer and Helwig 1925; Hann and Veale 1910; Humphreys and Halpert 1931; Wertham 1932) have been observed in the liver. In addition to these effects, altered prothrombin time or level has been observed in a number of individuals ingesting a single dose of white phosphorus (Caley and Kellock 1955; Dathe and Nathan 1946; Ehrentheill957; Fletcher and Galambos 1963; McCarron et al. 1981). Prothrombin and other plasma proteins that are required for the efficient progression and regulation of blood coagulation are primarily synthesized in the liver. A deficiency of these proteins is often observed in individuals with severe liver disease. A prolongation of prothrombin time is in part due to this impaired synthesis. Liver function tests were normal in workers chronically exposed to unreported levels of airborne phosphorus (Hughes et al. 1962). Similar hepatic alterations have been observed in animals acutely exposed to white phosphorus. Increases in AST and ALT levels (Paradisi et al. 1984), impaired liver function tests (Ghoshal et al. 1969; Hurwitz 1972; Sigal et al. 1954) increased liver weight (Ghoshal et al. 1969; Seakins and Robinson 1964), increased hepatic triglyceride levels (Ghoshal et al. 1969; Pani et al. 1972; Paradisi et al. 1984; Seakins and Robinson 1964), decreased protein synthesis (Barker et al. 1963; Seakins and Robinson 1964), disaggregation of polyribosomes (Pani et al. 1972), fatty degeneration (Ghoshal et al. 1969) and necrosis (Ghoshal et al. 1969) have been observed. No NOAEL values for hepatic effects following acute animal exposure were identified. In rats, the LOAEL value for liver effects was 6 mg/kg (Barker et al. 1963); in mice it was 5 mgkglday (Hurwitz 1972); and in dogs it was 0.2 mg/kg/day (Sigal et al. 1954). The liver effects occurred shortly after dosing; 3 hours after dosing, a significant decrease in protein synthesis was observed in the liver (Barker et al. 1963), minimal hepatocytic fatty changes were observed after 4 hours (Ghoshal et al. 1969), and severe hepatocytic fatty changes were observed after 12 hours (Ghoshal et al. 1969). The following hepatic effects have been observed in animals orally exposed for an intermediate duration fatty infiltration in guinea pigs exposed to 0.75 mg/kg/day (Ashbum et al. 1948), presence of eosinophilic granules at 0.25 mg/kg/day and cirrhosis at 0.66 mg/kg/day in rabbits and guinea pigs (Mallory 1933), and fibrosis and cirrhosis in pigs exposed to 0.6 mg/kg for 5 days/week (Peterson et al. 1991). In the Peterson et al. (1991) study, no liver effects were observed after 4 weeks of exposure; after 8 weeks, there were early signs of fibrosis, and after 12 weeks, extensive fibrosis was observed. Exposure to 0.075 mg/kg/day for an intermediate duration resulted in slight-to-moderate liver necrosis in dying pregnant rats (Bio/dynamics 1991), but no hepatic effects in the surviving pregnant rats or in male rats (Bio/dynamics 1991). In another reproduction study, liver effects were not observed in dying pregnant rats exposed to 0.075 mg/kg/day (IRDC 1985). Both studies used similar exposure protocols and similar vehicles; the difference in the occurrence of liver damage between the studies cannot be explained. Renal Effects. Evidence of severe renal effects have been observed in a number of individuals intentionally or accidentally ingesting a single dose of white phosphorus contained in rat (or roach) poison or fireworks. Proteinuria (Matsumoto et al. 1972; Pietras et al. 1968; Rao and Brown 1974), albuminuria (Dathe and Nathan 1946; Diaz-Rivera et al. 1950; Dwyer and Helwig 1925; Fletcher and Galambos 1963; McCarron et al. 1981; Rubitsky and Myerson 1949), acetonuria (Pietras et al. 1968), increased urobilinogen (Matsumoto et al. 1972), oliguria (Dathe and Nathan 1946; McCarron et al. 1981; Rao and Brown 1974), increased blood levels of urea and/or nitrogen (Diaz-Rivera et al. 1950, 1961; McCarron et al. 1981; Newburger et al. 1948; Pietras et al. 1968; Rao and Brown 1974; Rubitsky and Myerson 1949), and increased blood creatinine levels (Dathe and Nathan 1946; McCarron et al. 1981) have been observed in these individuals. Renal insufficiency may be due to a direct toxic effect of phosphorus on the kidneys or to acute renal tubular necrosis from fluid loss and shock. Patients in shock may have a peculiar pallor and cyanosis. These probably reflect extensive cellular damage with poor perfusion of the capillary beds, and are a prognostic sign of serious health effects (Melamon et al. 1981). Several case reports have reported no alterations in kidney function (Ehrentheil 1957; Fletcher and Galambos 1963; Greenberger et al. 1964; Simon and Pickering 1976). Histological alterations have also been observed in a number of humans ingesting a single dose of white phosphorus. Fatty changes in the tubules and loop of Henle (Dwyer and Helwig 1925; Humphreys and Halpert 1931; Wertham 1932) and engorged glomeruli and intratubular capillaries (Wechsler and Wechsler 1951) have been observed. Because most individuals vomited shortly after ingesting the white phosphorus or were lavaged, accurate doses cannot be calculated except for one study (Harm and Veale 1910). Histological alterations in the kidney were observed in an individual ingesting 2 mg/kg/day, but the lesion was not described. Creatinine levels were similar among unexposed workers and workers exposed to white phosphorus for chronic durations (Hughes et al. 1962). In animals, fatty infiltration in the nephron and subcapsular hemorrhages were observed in dogs acutely exposed to an unspecified amount of white phosphorus (Dwyer and Helwig 1925). No renal effects were observed in rats exposed to 0.075 mg/kg/day for an intermediate duration (Bio/dynamics 1991; IRDC 1985). No chronic exposure animal studies examining renal effects were located. Dermal Effects. Transient toxic dermatitis (described as a scalartiniform rash) developed 9 days after a man ingested a near-fatal dose of rat poison (Dathe and Nathan 1946). Edema of eyelids was reported in a 13-month-old child after ingestion of a fatal dose of white phosphorus (Rao and Brown 1974). Subcutaneous hemorrhages were visible in the left foot in a woman after consumption of 3.9 g of rat poison containing 4% phosphorus (Hann and Veale 1910). The woman died 4 days after the initial poisoning. At this time, an enormous subcutaneous hemorrhage was visible below the waist line. In this case report, the woman apparently did not expel (via vomiting) any of the ingested dose. Thus, it is likely that the ingested dose (2 mg/kg) was representative of the effective dose. Scattered blue-green petechiae were observed on the abdomen of a male child following accidental ingestion of a fatal dose of white phosphorus mixed with other ingredients from a firecracker (Humphreys and Halpert 1931). The dose level in this study could not be determined; the firecracker was a red composition of phosphorus mixed with other ingredients and was thought to contain about 10% phosphorus (Humphreys and Halpert 1931). No studies were located regarding dermal effects in animals after oral exposure to white phosphorus. Other Systemic Effects. A number of other systemic effects have been observed in humans ingesting a single dose of white phosphorus. The effects that are observed most consistently are hypoglycemia (Diaz-Rivera et al. 1950; McCarron et al. 1981; McIntosh 1927; Wechsler and Wechsler 1951), an increase in body temperature (mild pyrexia or fever) (Dathe and Nathan 1946; McIntosh 1927), and a decrease in plasma calcium, potassium, and/or sodium levels (Caley and Kellock 1955; McCarron et al. 1981; Rao and Brown 1974). It is unclear whether the fever seen is a symptom of phosphorus poisoning or a result of the treatment involved. In addition to these effects, metabolic acidosis (Rao and Brown 1974), hypothermia (Simon and Pickering 1976), damage to the spleen (Greenberger et al. 1964), ascites (Fletcher and Galambos 1963), fatty infiltration of the pancreas (Humphreys and Halpert 193 l), and necrosis of the adrenal medulla and cortex (Wechsler and Wechsler 1951) have been observed. In a child ingesting 0.083 mg/kg/day white phosphorus for an intermediate duration, decreased appetite, impaired body weight gain, and poor turgor (fullness or tension produced by the fluid content of blood vessels, capillaries, and cells) were observed (Sontag 1938). Serum glucose levels were decreased in workers occupationally exposed to white phosphorus for a chronic duration. It is likely that the workers were exposed by the inhalation, oral, and dermal routes (Ward 1928). In dogs acutely exposed to an unspecified amount of white phosphorus, hypoglycemia was observed (Williamson and Mann 1923). Rats received intermittent exposure to the atmosphere in the furnace room of a phosphorus factory for 14 months (Ruzuddinov and Rys-Uly 1986). Histology of rats killed monthly revealed progressive morphological degeneration of the tongue and oral mucosa of the cheek, gum, and hard palate. Epithelium and connective tissue from different parts of the oral cavity responded similarly to the treatment. Changes in the epithelial layer, observed after only 1 month of exposure, included increases in keratinization and numbers of cell layers, resulting in thickening and hyperkeratosis in the epithelium of the mucosa. Over time, the thickening and hyperkeratosis in the epithelium increased and histological changes were observed in the subepithelial connective tissue base. Eventually, the oral cavity contained areas of thickening of the mucosa from hyperkeratosis and increased epithelial cell layers interspersed with areas of decreased thickness of the epithelial layer due to atrophy, dystrophy, and cellular necrosis. At this time, adverse changes in the subepithelial connective tissue were considered pronounced. These effects occurred in most of the animals exposed to the atmosphere. It is likely that the observed effects of phosphorus on the oral cavity were local rather than systemic, resulting from direct contact of white phosphorus with tissues in the mouth. The study presented essentially no quantitative data, and the types and exposure levels of chemicals in the atmosphere (thought to contain elementary phosphorus and its inorganic compounds) were not reported (Ruzuddinov and Rys-Uly 1986). 2.2 DISCUSSION OF HEALTH EFFECTS BY ROUTE OF EXPOSURE
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Market Scenario The Enterprise File Synchronization and Sharing Market Size is growing rapidly. Market growth attributes to the rising adoption of enterprise adopt synchronization sharing (EFSS) technologies in businesses. Besides, the increasing need to protect data from consumer-based apps to store access and merge corporate data outside of the IT department foster market growth. Moreover, increasing numbers of businesses worldwide, escalate the growth of the market. According to Market Research Future (MRFR), the global enterprise file synchronization sharing market is expected to garner a valuation of around USD 11 BN by 2023, growing at approximately 28% CAGR throughout the forecast period (2017 to 2023). Increasing digitalization in file sharing solutions and business processes boost the growth of the market. Rising BYOD trends to improve work efficiency and reduce the company s operational expenses impact the market growth positively. COVID-19 Analysis The business impact of SARS-CoV-2 has been felt across diverse sections of the information technology industry, albeit at different levels. Companies in the technology sector that supply services for verticals like travel, retail, hospitality, and entertainment have noted a dramatic decrease in sales, while the firms that provide services related to remote worker solutions have observed the opposite. Enterprise File Synchronization Sharing Market ’s fate post pandemic has been relatively less grim compared to Education Services (ES) and Professional Services (PS) that are mostly dependent on components that are generally on-site. In a nutshell, COVID-19 impact on managed services has been fruitful, with the market growth enhanced than before. Given the prevalent lockdown situation, managed services vendors are now investing heavily in remote-centric worker solutions, which can make the market highly resilient in the coming years, even as the world is currently rushing to achieve a COVID-19 breakthrough. Request a Free Sample @ https //www.marketresearchfuture.com/sample_request/6294 Competitive Outlook Players leading the enterprise file synchronization sharing market include Microsoft Corporation (US), Dropbox (US), Citrix Systems (US), IBM Aspera (US), BlackBerry (Canada), VMware Inc. (US), OpenText (Canada), Google Inc. (US), Thru. Inc. (US), Egnyte (US), Syncplicity (US), Acronis International (Switzerland), SkySync (US), j2 Global (US), HighQ Solutions (UK), ownCloud (Germany), Nextcloud (Germany), CodeLathe (FileCloud) (US), Qnext Corp. (FileFlex) (Canada), Intralinks (US), XMedius Solutions (Canada), Northbridge Secure Systems (Australia), Inspire-Tech (Singapore/US), Wanpath LLC (US), CTERA Networks (Israel/US), and Accellion (US), among others. Segmentation By Component Standalone EFSS Solution, Integrated EFSS Solution, and others. By Deployment Type On-Cloud and On-Premises. By Organization Size Large Enterprises and small medium-sized enterprises (SMEs). By Vertical BFSI, Software Technology, Government Public Sector, Healthcare, Legal, Education, Retail, Media Entertainment, and others. By Regions Europe, North America, APAC, and Rest of the World. Regional Analysis Europe dominates the global enterprise file synchronization sharing market. The leading market share attributes to the continuous adoption of the latest technological advancements, such as integrating cloud and mobile technologies within traditional enterprise file sharing and synchronization solutions. Also, early adoption and constant innovation by the organizations substantiate the growth of the regional market. The European enterprise file synchronization sharing market is projected to retain its dominance throughout the estimated period. North America stands second in the global enterprise file synchronization sharing market. The market is driven by the presence of several notable players and well-equipped infrastructure that allows development and early adoption of technologies. The US and Canada are the key growth contributors to the regional market. Additionally, various dynamic diversified multinational organizations foster the growth of the regional market. The North American enterprise file synchronization sharing market is expected to create a substantial revenue pocket during the forecast period. Table of Contents 1Executive Summary 2Scope of the Report 2.1Market Definition 2.2Scope of the Study 2.2.1Research objectives 2.2.2Assumptions Limitations 2.3Markets Structure Continued…. Browse Full Report Details @ https //www.marketresearchfuture.com/reports/enterprise-file-synchronization-sharing-market-6294 List of Tables Table1 Global Enterprise File Synchronization Sharing Market, By Region, 2020–2027 Table2 North America Enterprise File Synchronization Sharing Market, By Country, 2020–2027 Table3 Europe Enterprise File Synchronization Sharing Market, By Country, 2020–2027 Continued… List of Figures FIGURE 1 Global Enterprise File Synchronization Sharing Market Segmentation FIGURE 2 Forecast Methodology FIGURE 3 Porter’s Five Forces Analysis Of Global Enterprise File Synchronization Sharing Market Continued… Trending #MRFR Report** https //ictmrfr.blogspot.com/2022/04/geofencing-market-companies-growth-with.html https //blogfreely.net/pranali004/telecom-expense-management-market-size-impressive-cagr-changing-business-scope https //postheaven.net/pranali004/financial-app-industry-impressive-cagr-changing-business-needs-scope-of https //market-research-future.tribe.so/post/openstack-service-market-research-impressive-cagr-changing-scope-of-current--6263de46791566c10c79891e https //www.scutify.com/articles/2022-04-24-infrastructure-as-a-service-industry-cagr-changing-business-scope-of-current-and-future-industry- About Market Research Future Market Research Future (MRFR) has created a niche in the world of market research. 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We handle 13 industry verticals including Healthcare, Chemicals and Materials, Information and Communications Technology, Semiconductor and Electronics, Energy and Power, Food, Beverages Nutrition, Automobile, Consumer and Retail, Aerospace and Defense, Industrial Automation and Equipment, Packaging Transport, Construction, and Agriculture. With our unique approach for every market report, we aim to reach the zenith in qualitative business intelligence and syndicated market research. Contact Market Research Future (Part of Wantstats Research and Media Private Limited) 99 Hudson Street, 5Th Floor New York, NY 10013 United States of America 1 628 258 0071 (US) 44 2035 002 764 (UK) Email sales@marketresearchfuture.com Website https //www.marketresearchfuture.com